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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

Author

G. Alfonsín

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Open access Jul 2026

E3 ubiquitin-ligase Hakai regulates LRP4 stability and Wnt/β-catenin signalling in colorectal cancer cells

Mechanistically, the findings support that Hakai regulates LRP4 stability, a negative regulator of Wnt signaling, consistent with ubiquitin-dependent mechanism, and highlight Hakai inhibition as a potential CSC-directed therapeutic strategy in colorectal cancer.

Andrea Rodríguez-Alonso, Lía Jove, G. Alfonsín et al. · 0 citations

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