Open access
Sep 2026
Live-cell transcriptomics with engineered virus-like particles
SUMMARY Transcriptomic profiling is widely applied to characterize cellular gene expression, yet existing approaches lyse cells and preclude direct analysis of transcriptional dynamics in the same sample over time. We addressed this limitation by engineering mammalian cells to “self-report” their transcriptional states...
M. Najia, Anna Le, Jacob Borrajo et al.
· Cell · 0 citations