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Fumito Mori

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Open access Jul 2026

Additive framework of hormonal waves accounts for species and age differences in circadian intraocular pressure rhythm

A minimal mathematical framework in which IOP rhythms arise from the linear superposition of two sinusoidal signals: adrenal glucocorticoids and norepinephrine from the superior cervical ganglion is developed, which provides a unifying conceptual basis for the circadian regulation of IOP across species and may inform novel diagnostic algorithms and chronotherapeutic strategies for glaucoma.

Keisuke Ikegami, Ryo Fujie, Fumito Mori et al. · 0 citations

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