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Fu-Zheng Zou

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Open access Sep 2026

pH-responsive Zn2+-coordinated gellan gum/γ-polyglutamic acid hydrogel microspheres as functional biomaterials for intra-articular delivery: physicochemical design, smart release, and chondroprotective performance in osteoarthritis

Findings establish PGG-Zn@Cur as a microenvironment-responsive intra-articular platform that maintains cartilage matrix homeostasis and alleviates PI3K-AKT-associated apoptosis-related responses, offering a promising strategy for disease-modifying OA therapy.

Kai-Ming Zhang, Hao-Nan Xue, Xiang-Wei Li et al. · 0 citations

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