The repair of critical-sized bone defects is hindered by insufficient vascularization, an unfavorable osteogenic microenvironment, and the limitations of conventional materials. Systematic studies on ternary composites of graphene oxide (GO), calcium alginate (CA), and strontium-doped hydroxyapatite (Sr-HA) remain limi...
Chun-Quan Ma, Xu-Dong Wu, Ze-La-Lai-Di A. Li et al.· Biofabrication· 0 citations
Alveolar ridge deficiency remains a significant clinical challenge in dental implantology, often necessitating bone augmentation procedures. While autogenous bone grafting is considered the gold standard, its limitations, including donor site complications and limited availability, have prompted the development of alte...
A. Mohetaer, Shan Rong, Jing Zhang et al.· Macromolecular Bioscience· 0 citations
Overall, PTB4 achieved the best balance among printability, mechanical compatibility, cytocompatibility, angiogenesis-related activity, and osteogenic performance, supporting low-dose BT modification as a promising strategy for safe, printable scaffolds for critical-size craniofacial and oral bone defect repair.
