Author

Frederick Lo

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Open access Oct 2026

Dynamic remodeling of the KRAS interactome by direct RAS inhibitors with distinct mechanism of action reveals convergent responses

It is demonstrated that KRAS is a central node in regulating growth factor-induced cell migration, and that KRAS inhibition plays a broader role than MAPK-mediated cell proliferation and survival.

Yang Yang, Ting-Yu Liu, Charles Y. Cho et al. · Oncogene · 0 citations