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Fred O Ede

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Open access Aug 2026

Peptide exchange–competent class I MHC molecules produced in eukaryotic cells for rapid production of MHC multimers

A novel method is presented for the expression in eukaryotic cells of secreted peptide exchange–competent class I MHC proteins in their native conformation and it is demonstrated that tetramers produced in this way are equivalent to conventionally produced tetramers for T-cell staining.

V. Ramachandiran, J. Shires, Richard A. Willis et al. · 0 citations

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