Francesca Mangili

Integrating Genomic Annotations and Traits Dependencies for single-nucleotide polymorphisms Prioritization with Causal Concept Bottleneck Models

A modeling approach that combines genomic annotations with known cross-trait relations by leveraging Causally Reliable Concept Bottleneck Models (C2BM), a deep learning architecture that factors the joint trait distribution over a graph of interpretable concepts allows trait predictions to leverage information from oth...