TRPM4 contributes to the formation and outgrowth of Dukes' stage C colorectal cancer tumor spheroids.
Colorectal cancer (CRC) is a leading cause of cancer-related deaths, with disease progression and distant metastasis being the major determinants of mortality. The ion channel transient receptor potential melastatin-4 (TRPM4) has been associated with several types of cancer and has been shown to regulate key cellular f...