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Author

Filippo Ruffini

4 papers indexed here

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Preprint Oct 2026

NoduleFlow: Automatic 3D Lung Nodule Detection and Segmentation

Low dose Computed Tomography (CT) is the standard imaging modality for lung cancer screening. On CT scans, lung cancer typically manifests as pulmonary nodules, whose manual identification is time-consuming and prone to observer variability, image quality limitations, and suboptimal reading conditions. Moreover, subtle...

G. Romoli, Filippo Ruffini, Francesco Di Feola et al. · 0 citations
Open access Sep 2026

Benchmarking foundation models for tumor segmentation across multiple cancer types

The robustness analysis reveals a trade-off: MedSAM tolerates prompt perturbations, while Medical SAM 2 achieves higher accuracy but degrades under box tightening and spatial shifts, supporting the use of SAM-based models for multi-cancer segmentation, while showing that reliability depends on prompt quality and anatom...

M. Tortora, Elena Mulero Ayllón, Filippo Ruffini et al. · 0 citations

Cross Modality Image Translation In Medical Imaging Using Generative Frameworks

This work presents a reproducible benchmark for 3D I2I translation in oncological imaging that compares seven generative models: three Generative Adversarial Networks (Pix2Pix, CycleGAN, and SRGAN) and four latent models (Latent Diffusion Model, Latent Diffusion Model+ControlNet, Brownian Bridge, and Flow Matching).

G. Romoli, A. Capoccia, Filippo Ruffini et al. · 1 citation
#artificial intelligence Preprint Sep 2026

Source Anchoring for Physical Consistency in Flow Matching Models

This work proposes Source Anchoring for Physical Consistency (SAPC), a Functional Flow Matching method that encodes the physical constraints into the source noise before generation begins, and identifies the source distribution as a key design choice for physically consistent generative modelling.

G. Romoli, Filippo Ruffini, P. Soda · 0 citations

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