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Filipe Oliveira-Brás

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Open access Oct 2026

Hyperglycemia-induced metabolic rewiring is associated with skeletal muscle loss in a fructose-streptozotocin-induced diabetic rat model.

AIMS This study investigated the impact of hyperglycemia on systemic and skeletal muscle metabolite profiles. METHODS Serum and gastrocnemius metabolites of fructose-fed, streptozotocin-injected rats (T2D) were analyzed by 1H NMR and related to markers of energy metabolism and mitochondrial remodeling. RESULTS T2D...

Alexandra Moreira-Pais, Filipe Oliveira-Brás, Rúben J. Moreira et al. · 0 citations

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