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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Ferdaous Elandaloussi

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Open access Sep 2026

N‐(1H‐Indazolyl) Aryl Sulfonamide Hybrids as Potential Dihydropteroate Synthase Inhibitors: In Vitro Antibacterial Activity Against Escherichia coli and Staphylococcus aureus and Computational Modeling

Structural–activity analysis showed antibacterial efficacy is governed by aryl sulfonyl electronic effects, steric balance at the C7 indazole position, and physicochemical properties affecting Gram‐negative membrane permeability, supporting indazole–sulfonamide hybrids as promising scaffolds that may retain predicted b...

Romaisaa Boudza, Ferdaous Elandaloussi, Khalid Boujdi et al. · 0 citations

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