Multi-Omics Analyses Reveal Expression Remodeling of Key Glycolytic-Lactate Metabolic Nodes in the Pituitary of High-Altitude Sheep.
BACKGROUND Most studies of high-altitude adaptation in animals have focused on the heart, lung, blood, and skeletal muscle, whereas systematic evidence regarding metabolism-related expression changes in the pituitary remains limited. The pituitary is an energy-demanding neuroendocrine organ characterized by active gluc...