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Open access Sep 2026

Patient-derived organoids enable ex vivo drug-response profiling for precision medicine in bladder cancer

Patient-derived organoids (PDOs) represent a promising precision medicine approach for replicating primary tumor characteristics and facilitating drug testing across various cancers, although clinical evidence in bladder cancer remains limited. This study evaluates the impact of incorporating PDOs into clinical pract...

Si-Jia Li, Feng Qiu, Fang-Yue Zheng et al. · 0 citations
Open access Aug 2026

m6A‐Mediated Stabilization of MRPS23 Drives NSCLC Progression Via HSPA8 and ERK Signaling Modulation

ABSTRACT Lung cancer remains the leading cause of cancer‐related mortality worldwide, largely due to therapeutic resistance and tumor progression. Mitochondrial ribosomal proteins (MRPs), particularly MRPS23, have recently emerged as critical regulators of cancer progression in various malignancies, while N6‐methyladen...

Si-Hong Le, Y. Le, Xianshen Sha et al. · 0 citations

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