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Review Open access Oct 2026

Tryptophan metabolism within the gut-brain axis in depression: mechanisms, association with heterogeneity, and therapeutic opportunities.

Depression is a highly heterogeneous psychiatric disorder, characterized by substantial variability in clinical manifestations, treatment responses, and disease progression, thereby posing significant challenges to precision diagnosis and therapeutic intervention. Accumulating evidence indicates that dysregulated trypt...

Zhi-Jun Qin, Ting Lei, Tao Yi et al. · 0 citations

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