Negative regulation of suppressor of cytokine signaling 3a and 3b for antibacterial immunity in Cyprinus carpio infected by Aeromonas hydrophila.
Suppressor of Cytokine Signaling 3 (SOCS3) plays a crucial negative regulatory role in maintaining immune homeostasis, but its function in the antibacterial immunity of common carp Cyprinus carpio remains unclear. In this study, Ccsocs3a and Ccsocs3b were cloned and identified in C. carpio for the first time. Their seq...