Nanozyme-based catalytic therapy triggered by tumor-specific endogenous stimuli is an emerging tumor therapy that has attracted significant attention. Nevertheless, the efficacy of current catalytic therapies is severely limited by the intrinsic catalytic efficiency of nanozymes and the low concentration of endogenou...
Lu Zhao, Liang Zhu, Chao-Yu Wang et al.· ACS Omega· 0 citations
Catalytic ferroptosis therapy provides an attractive approach for tumor treatment, but its practical efficacy is often limited by insufficient reaction kinetics and the strong redox buffering capacity of the tumor microenvironment. Herein, we report an interface-engineered 2D-on-2D catalytic nanoplatform, SNs/FTC@Apt...
Hui Xu, Rong-Jie Zhang, Lu Zhao et al.· Molecular Pharmaceutics· 0 citations
The designed nanobomb integrates targeted delivery, pH responsiveness, fluorescence imaging, and amplified PDT-CDT-CHT triple-action tumor annihilation into a single system, providing a promising strategy for tumor diagnosis and treatment.