Keratin 18 as a cytoskeletal regulator of epithelial–mesenchymal plasticity and prognostic risk in oral squamous cell carcinoma
Background/purpose Oral squamous cell carcinoma (OSCC) shows poor survival, and conventional staging does not fully capture biologic aggressiveness. Keratin 18 (KRT18) has been linked to malignant progression in epithelial cancers, but its prognostic and biologic significance in OSCC remains unclear. This study investi...