Background/Aim: Esophageal squamous cell carcinoma (ESCC) is aggressive and has a poor prognosis. RNA-binding protein FXR1 contributes to tumor progression, but its role and mechanism in ESCC remain largely unclear. This study aimed to explore the expression, prognostic value, and molecular mechanism of FXR1 in ESCC. M...
Xiao-Li Wang, Qian-Wen Miao, Xiao-Yuan Liu et al.· Anticancer Research· 0 citations
Antibody-drug conjugates (ADCs) have become the standard treatment for HER2-positive(HER2+)advanced breast cancer following the failure of trastuzumab or taxane. Nevertheless, there are no direct head-to-head trials comparing different ADCs.
We searched PubMed, Embase, the Cochrane Library and abstracts from...
Fen Liu, Yong Pan, Jin-Lan Li et al.· Frontiers in Pharmacology· 0 citations
Taxanes play pivotal roles across therapeutic stages of triple-negative breast cancer (TNBC), yet their efficacy is substantially limited by drug resistance and systemic toxicity. Immunotherapy has been found to enhance the efficacy of chemotherapy. Here, we investigated the synergistic antitumor activity between tax...
Rong Ma, Ying Zhou, Tian-Tian Yu et al.· Cell Death & Disease· 0 citations
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