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Felipe Velasquez Moros

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Open access Sep 2026

PURELIGHT: a quantitative photon-counting framework unifying intensity and lifetime imaging at video rate across detector technologies

Quantitative fluorescence microscopy requires photon-efficiency, speed and accurate intensity and lifetime measurements. Time-correlated single-photon counting (TCSPC) simultaneously captures intensity and lifetime, but photon pile-up distorts both signals at high count rates, preventing fast acquisitions. Existing cor...

Felipe Velasquez Moros, Dorian Amiet, Daria Skwarzynska et al. · 0 citations

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