Open access
Oct 2026
In situ architecture of the basal body reveals regionalized assembly and central pair microtubules nucleation
The basal body (BB) is essential for axoneme assembly and ciliary function, and its defects are associated with ciliogenesis disorders and ciliopathies1,2. However, the molecular basis of the BB’s region-specific transitions along the proximal-distal axis, and the mechanism by which ciliary central pair (CP) microtubul...
Zi-Yang Wang, Huan Yang, Hao Lang et al.
· bioRxiv · 0 citations