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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Fei He

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Open access Sep 2026

Local acetyl-CoA metabolism and acetate recycling as epigenetic regulators of chromatin dynamics

Abstract Histone acetylation depends on acetyl-CoA, a central metabolic intermediate linking nutrient availability to chromatin regulation. Beyond bulk acetyl-CoA abundance, accumulating evidence indicates that chromatin-proximal acetyl-CoA production and acetate recycling provide spatial control over histone acetylati...

Jueun Kim, Fei He, Shan-Shan Li et al. · 0 citations

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