Fluorescence-guided surgery requires tumor-imaging probes that provide reliable contrast while minimizing background interference. Herein, we developed a gastrin-releasing peptide receptor (GRPR)-targeted near-infrared (NIR) fluorescent probe, IR783-BBN, by covalently conjugating the bombesin peptide with the IR783 flu...
Radio imaging and optical imaging offer complementary advantages for biomedical diagnosis. However, the photosensitizers used in imaging must be degraded to reduce phototoxicity during phototherapy. Herein, we report a novel dicyanomethylene-based near-infrared photosensitizer (PS) that self-degrades via multiple pathw...
Hong-Yu Chen, Ji Feng, Yuan Ma et al.· ACS Applied Materials and In...· 0 citations
Chemotherapy for advanced breast cancer may promote metastatic progression through inflammatory responses. To address this challenge, we developed carrier-free Cur/DTX@ICG nanoparticles via molecular co-assembly, achieving a high drug-loading capacity of 66.7%. This theranostic platform integrates docetaxel, curcumin,...