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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Federica Pellati

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Open access Sep 2026

CX3CL1-CX3CR1 signaling shapes the sex- and region-dependent neuroimmune response to LPS: Impact on plasticity and kynurenine pathway metabolism in the hippocampus.

BACKGROUND Fractalkine signaling is a central mediator of neuron-microglia communication. We previously demonstrated that, under physiological conditions, the fractalkine receptor (CX3CR1) differentially modulates synaptic plasticity along the dorsoventral axis of the hippocampus in male but not in female mice. During...

Eleonora De Felice, Giovanni Signorini, Laura Bertarini et al. · 0 citations

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