Adverse-effect burden as the dominant correlate of antidepressant non-adherence in major depressive disorder: insights from a multicentre machine-learning analysis.
BACKGROUND Non-adherence to antidepressants contributes to relapse and recurrence in major depressive disorder (MDD). Existing risk-prediction models are drawn largely from chronic conditions in high-income settings; none exist for Pakistani outpatient psychiatry. METHODS We analysed cross-sectional, patient-reported...