Fatma Güzel

The N-terminal, WD40, and C-terminal domains of WDR-31 control ciliary localization and cooperate with ELMOD/RP2 gaps to maintain membrane compartmentalization

Background/aim WD40 repeats are found in many ciliary proteins. Although the WD40 repeat-containing WD repeat-containing protein 31 (WDR-31) is known to regulate ciliary protein trafficking and morphology, the specific contributions of its N-terminal, WD40, and C-terminal domains to protein localization and ciliary gat...