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Author

Farshad Ghasemi

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Jul 2026

Pentoxifylline, as nonselective phosphodiesterase inhibitor, attenuate paraquat-induced hepatic damage: in vivo and molecular docking insights

PTX administration may prevent PQ-induced hepatic damage in mice, potentially by inhibiting free radical formation and molecular docking analysis suggests that PTX may reduce PQ-induced oxidative stress by competitively inhibiting the FAD-binding site of xanthine oxidase, and by engaging a non-active-site region of NADPH oxidase.

Mobin Mohammadi, Farshad Ghasemi, Fatemeh Ghaffari et al. · 0 citations

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