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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

Author

F. Isaacs

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Open access Sep 2026

Engineered Orthogonal Translation Systems from Metagenomic Libraries Expand the Genetic Code

Genetic code expansion with noncanonical amino acids (ncAAs) opens new opportunities for the design and engineering of proteins by broadening their chemical repertoire. Unfortunately, ncAA incorporation into proteins is limited both by a small collection of orthogonal aminoacyl-tRNA synthetases (aaRSs) and tRNAs and...

Kosuke Seki, Michael T. A. Nguyen, Petar I. Penev et al. · 0 citations
Open access Jul 2026

Cas3-mediated genome reduction: demonstration in Cupriavidus necator H16 improves growth on heterotrophic and autotrophic carbon sources

A Cascade–Cas3-enabled method called TRIM3 is reported that generates large deletions by targeting a randomly integrated transposon, enabling facile generation of a genome-reduced mutant library and represents a new avenue for large-scale genome modifications and the development of improved bioprocessing hosts.

E. Fulk, R. M. Swart, Akira K Nakamura et al. · 0 citations
Open access Aug 2026

Systematic prioritization of candidate genes in camptothecin biosynthesis using multi‐omics and deep learning

This study engineered an experimental callus system for inducible production of CPT, which enabled multi‐omics and deep learning analyses to identify candidate genes in CPT biosynthesis and provides a valuable foundation for the complete elucidation of the CPT biosynthetic pathway.

Shenqiu Wang, Xing Wu, Maria Moreno et al. · 0 citations

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