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Fangluo Chen

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Open access Aug 2026

Deep phenotyping and multi-omics analyses reveal systems-wide metabolic dysregulation in a refined trisomy mouse model of Down syndrome

Deep phenotyping and multi-omics analyses showed that Ts66Yah mice develop pronounced and widespread metabolic disturbances, establishing Ts66Yah as a valuable reference model for the mechanistic and comparative study of metabolic dysfunction in DS.

Muzna Saqib, Fangluo Chen, Diya K. Mistri et al. · 0 citations

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