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Author

Fang-Yuan Xiong

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Sep 2026

SET Interacts With CENP-A and HJURP to Ensure Proper Mitotic Progression in Human Cells.

Centromeres are specialized chromosomal loci that ensure faithful chromosome segregation during mitosis, a function that depends on the precise localization of the histone H3 variant centromere protein A (CENP-A) within centromeric chromatin. CENP-A deposition is tightly regulated by assembly factors, including HJURP;...

Ying Wang, Cheng-Cheng Hu, Xin-Yang Wang et al. · 0 citations
Open access Aug 2026

MAD2B guides chromosome stability in mitosis via the MAD2B-CIP2A signaling axis.

Error-free mitosis depends on accurate chromosome attachment to spindle microtubules, monitored by the spindle assembly checkpoint machinery, which prevents precocious chromosome segregation and reduces the risk of aneuploidy. MAD2B, a homologue of MAD2, is critical for mitotic quality control and DNA damage repair. Ho...

Umer Ejaz, Fang-Yuan Xiong, Hengyi Shao et al. · 0 citations

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