TIMS-MS combined with theoretical modeling for flavonoid isomer separation using cyclodextrin-metal ion ternary complexes.
In this study, ion mobility mass spectrometry (IM-MS) and theoretical modeling were used to identify flavonoid isomers. MS results showed that the isomers could not be distinguished based on their similar m/z values, fragment ions, or mobility values. β/γ-Cyclodextrin (CD) can interact with the isomers and improve thei...