Author

Fan Yang

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Open access Oct 2026

IGF2BP1 in 17q-gain cooperates with MYCN to regulate purine biosynthesis and immunotherapy efficacy in neuroblastoma.

An IGF2BP1/MYCN-PAICS-CHK1 axis that drives aggressive neuroblastoma phenotypes and constitutes an actionable vulnerability for therapeutic intervention is identified.

Jia-Xu Liu, Ying-Zhe Fang, Rong-Rong Fan et al. · Proceedings of the National... · 0 citations