Sep 2026
Sequential lysosome-microtubule targeted transformable nanosystem for long-lasting photodynamic-based multimodal therapy of breast cancer.
Subcellular organelle-targeted strategies hold great promise in cancer therapy. Peptide nanofibers can induce lysosomal membrane permeabilization (LMP) and microtubule disruption, yet their in vivo delivery remains challenging. Here, we report a matrix metalloproteinase-2 (MMP-2)-responsive shape transformable nanosyst...
Ru-Yi Lin, Li Xia, Ya-Tong Zhang et al.
· Journal of Controlled Releas... · 0 citations