Review
Open access
Sep 2026
Peptide-Based Molecular Glues for Targeted Protein Degradation
This review examines the comparative advantages of peptide-based architectures, including reduced molecular weight, access to challenging interfaces, and expansion of the addressable E3 ligase repertoire, against persistent translational barriers in proteolytic stability, membrane permeability, immunogenicity, and manu...
Walaa S. Aburayan, Ibrahim A. Alradwan, Beshair A. Alsaffar et al.
· Pharmaceutics · 0 citations