Open access
Oct 2026
Untargeted Metabolomics via UPLC-HRMS and ASCA-Based Statistical Modeling to Characterize Metabolic Alterations Following Acute and Repeated Brorphine Exposure
Background: Novel Synthetic Opioids (NSOs) currently represent the third most prevalent group among New Psychoactive Substances (NPS), yet they represent the category associated with the highest health risk. Their extreme pharmacological potency compared to traditional opioids, coupled with structural heterogeneity and...
Ilenia Bracaglia, Ludovica Chiodo, C. Montesano et al.
· Metabolites · 0 citations