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Author

Fabian Zincke

2 papers indexed here

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Open access Sep 2026

MACC1 Hyperactivates Receptor Tyrosine Kinase Signaling Through Phosphorylation-Dependent Adaptor Activity in Colorectal Cancer Cells

Understanding the mechanisms of metastasis is one of the most pressing issues in cancer therapy. Metastasis-associated in colon cancer 1 (MACC1) is an important biomarker and functional driver of tumor progression and metastasis. However, the molecular mechanisms underlying its activity remain incompletely understood....

Fabian Zincke, D. Kobelt, Susan Kläger et al. · 0 citations
Open access Aug 2026

ZFP36L2 orchestrates stress-adaptive plasticity in regeneration and cancer

Together, these data show that ZFP36L2 acts as an important molecular switch that couples stress sensing with phenotypic plasticity, which in turn drives cellular dedifferentiation essential for re-establishing the ISC state during wound healing and metastasis.

Qi Jiang, Manisha S. Raghavan, Aileen M. Rodriguez et al. · 0 citations

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