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Open access Jan 2026

Antiplasmodial Activity of Methylangolensate From Entandrophragma angolense (Welw.) C.DC. Stem Bark: An In Vitro and In Silico Approach

Background Previous investigation of the antiplasmodial effects of methylangolensate (MAL) has revealed promising activity against multiple strains of Plasmodium falciparum parasites. However, a significant gap still remains to be bridged regarding its potential as a lead compound for the development of novel drugs for...

Jude Tetteh, Jemima Aggrey Appiah, F. Zoiku et al. · 0 citations
Open access Sep 2026

Antimalarial Potential of the Stem Bark of Amphimas pterocarpoides (DC.) Harms: In vivo Antimalarial Activity of Hydroethanol Extract and In Vitro Antiplasmodial Activity of Bioactive Constituents

Objective This study evaluated the antimalarial activity of the stem bark extract of Amphimas pterocarpoides, isolated bioactive compounds from its most active fraction, and assessed the interactions of these constituents with the Plasmodium falciparum lactate dehydrogenase (pfLDH) in silico. Methods The acute oral tox...

George Adjei-Hinneh, Evelyn Asante-Kwatia, A. Y. Mensah et al. · 0 citations

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