F. von Delft

Discovery of a molecular glue inhibitor that stabilises a non-productive Kalirin-Rac1 complex

The first OpenBind release: An open experimental structure–affinity dataset and benchmark for structure-based AI

High-quality experimental datasets that link protein–ligand structures with binding affinity data are essential for developing and evaluating structure-based machine learning methods. To help address this need, we established OpenBind as an open-science initiative to generate large-scale experimental datasets for struc...