Open access
Sep 2026
534. Striatal dopamine synthesis trajectory in first-episode psychosis during amisulpride monotherapy and after switch to aripiprazole: a one-year [18F]DOPA PET study
Abstract Background Schizophrenia and related psychotic disorders are associated with elevated striatal dopamine synthesis from the first episode. While antipsychotics primarily improve symptoms through dopamine D₂ receptor blockade, it remains unclear whether they affect presynaptic dopamine synthesis due to mixed fin...
S. Kim, J. Schubert, M. Veronese et al.
· International Journal of Neu... · 0 citations