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H74 is a benzothiazole derivative bearing a thiourea moiety molecule that was synthesized in our laboratory. The antioxidant activity and the potential effects of H74 on multiple targets associated with Alzheimer's disease (AD) were investigated. The anticholinesterase and the antioxidant activities of H74 were tested...
Results indicate an enzyme-dependent inhibitory profile rather than uniformly superior activity relative to the reference inhibitors, and quantum theory of atoms in molecules (QTAIM) analysis was performed to characterize selected intra- and intermolecular interactions.
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