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Author

F. Trudzinski

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2 papers indexed here

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Oct 2026

S2k-Leitlinie Fachärztliche Diagnostik und Therapie der COPD 2026

Zusammenfassung Die vorliegende S2k-Leitlinie aktualisiert die Empfehlungen zur fachärztlichen Diagnostik und Therapie der chronisch obstruktiven Lungenerkrankung (COPD) und ergänzt die Nationale VersorgungsLeitlinie COPD um spezialisierte diagnostische und therapeutische Handlungsempfehlungen. Grundlage sind die aktue...

K. Kahnert, Mustafa Abdo, Peter Alter et al. · 0 citations
Open access Oct 2026

Safety and pharmacokinetics of inhaled aloxistatin: A first-in-human phase 1 dose escalation trial.

AIMS Aloxistatin (E64d) is a membrane-permeable cysteine protease inhibitor prodrug that is converted by esterases to the active metabolite E64c (loxistatin). This first-in-human study evaluated the safety, tolerability and pharmacokinetics of single ascending doses of inhaled E64d in healthy volunteers. METHODS In t...

S. Fähndrich, Franziska Friedrich, Daniel Soriano et al. · 0 citations

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