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Author

F. Trogisch

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2 papers indexed here

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Open access Aug 2026

Early Cardiomyopathy in Prediabetic NDPK-B-Deficient Mice Is Associated with Remodeling of the Mitochondrial O-GlcNAc Proteome

Diabetic cardiomyopathy (DCM) is characterized by myocardial remodeling that may already be evident during prediabetes, yet the molecular alterations accompanying these early changes remain poorly understood. The present study examined mouse models of Nucleoside diphosphate kinase B (NDPK-B)-deficient prediabetes and s...

Noor Karim, Miao Qin, Rachana Eshwaran et al. · 0 citations
Open access Jul 2026

Reassessing Tcf21-iCre for Adult Cardiac Fibroblast Gene Deletion: Limited Recombination Efficiency Following Tamoxifen Injections

Tcf21-iCre cannot reliably achieve broad gene deletion in adult cardiac fibroblasts with i.p. tamoxifen injection, limiting its usability in loss-of-function studies that require broad fibroblast coverage and highlighting the need for alternative Cre-drivers or delivery strategies to facilitate antifibrotic therapy dev...

A. Schober, Lukas Müller, R. Wardman et al. · 0 citations

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