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Author

F. Sotty

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Open access Aug 2026

Multiple system atrophy-derived α-synuclein fibrils are more potent and display oligodendrocyte cell tropism compared to Parkinson's disease-derived fibrils.

Interestingly, amplified material from MSA brains induced significantly more oligodendroglial pSyn aggregates than amplified material from PD brains, and mice injected with the fibril polymorph, showed mild changes in microglial reactivity.

Anne-Line Strange Laursen, K. Willén, Alexis Fenyi et al. · 0 citations

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