Author

F. Sirajudeen

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Review Open access Aug 2026

From KRAS inhibition to tumor adaptation: mechanistic layers of resistance and therapeutic strategies.

This review synthesizes current knowledge on KRAS resistance mechanisms and highlights emerging therapeutic strategies, including rational combination approaches, enhanced RAS pathway suppression, targeted protein degradation, and KRAS-directed immunotherapies.

Rawan Salih, F. Sirajudeen, Mohamed Rahmani · Journal of Advanced Research · 0 citations