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Author

F. Seixas

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Open access Aug 2026

From comparative oncology to AI-enabled precision medicine: translational biomodels for triple-negative breast cancer

Triple-negative breast cancer (TNBC), defined by the absence of estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2 expression or amplification, comprises a biologically heterogeneous group of tumors with aggressive clinical behavior and limited biomarker-guided treatment options. Alt...

T. Collares, F. Seixas, C. Pessoa et al. · 0 citations
Review Open access Jul 2026

The cancer/testis antigens represent promising targets for the development of new therapies against melanoma.

This review aims to critically analyze the immunogenic and oncogenic potential of CTAs, synthesize current preclinical and clinical evidence across distinct CTA subfamilies, and highlight innovative CTA-based immunotherapeutic strategies for the treatment of melanoma.

Suzana Lemke Lanius, B. Pacheco, Fernanda Severo Sabedra Sousa et al. · 0 citations

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