Probing protein structures in solution via concentration- and temperature-dependent small- and wide-angle x-ray scattering.
Temperature-dependent small- and wide-angle x-ray scattering is developed as a probe of biomolecular structure, dynamics, and interactions in the solution phase and applied to two well-characterized model proteins: the Villin headpiece subdomain and the GB3 domain to provide real-space fingerprints of the folds that pl...