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F. Schmidt

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Open access Aug 2026

Human NLRC4 can act as a direct sensor for cytosolic flagellin

Innate immune cells sense pathogenic bacteria like Legionella pneumophila through patterns such as the protein flagellin, a critical component of the bacterial motility apparatus. Recognition of cytosolic flagellin in mouse immune cells is well understood and mediated by the receptors, neuronal apoptosis inhibitory pro...

Gaopeng Li, Kenyatta Doumanas, Xiao Liu et al. · 0 citations
Open access Jul 2026

A Picomolar MBP-Binding Nanobody for Target Enrichment and Modular Complex Engineering

The variable domains of heavy chain only antibodies, also called nanobodies, have provided powerful new tools for biomedical research. Their rapid development across multiple fields has helped address emerging scientific and clinical challenges, establishing single-domain antibodies (sdAbs) as highly adaptable platform...

M. Chinellato, Elisa Franzin, Filippo Vascon et al. · 0 citations

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