Author

F. Schleich

3 papers indexed here

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Open access Sep 2026

Assessing the impact of earlier initiation of biologics on clinical remission and other outcomes in a global real-life severe asthma cohort from CHRONICLE, ISAR and OPCRD.

BACKGROUND Biologics are generally reserved for severe asthma (SA) after standard treatments have failed. Their recommendation is based on randomized controlled trials, designed to assess efficacy but not the optimal timing for biologic initiation. RESEARCH QUESTION Does the timing of biologic initiation affect SA ou...

G. Canonica, G. Christoff, Ming-Ju Tsai et al. · Chest · 0 citations

Review Open access Sep 2026

Biologic outcomes in severe asthma patients by smoking status: evidence from SHARP.

RATIONALE The efficacy of biologics remains debatable in current or ex- smokers with severe asthma. OBJECTIVES This study aimed to evaluate responses to biologics by smoking exposure and to assess variations in management practice across Europe. METHODS This was a retrospective real-world study of adults with sever...

M. Caminati, J. Charriot, A. Bansal et al. · American Journal of Respirat... · 1 citation

Review Open access Sep 2026

Accuracy of type 2 inflammatory biomarkers to diagnose asthma in adults and children: a meta-analysis of 30 studies with prospective validation in an adult primary care cohort.

In both the meta-analysis and the DIVE cohort, FeNO diagnostic accuracy declined within 2 weeks of inhaled corticosteroid exposure, and FeNO thresholds correctly classifyied rule-in decisions and rule-out decisions.

Marc-André Roy, M. Gronnier, Laurence Désy et al. · The Lancet Respiratory Medic... · 1 citation