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Author

F. Pratto

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2 papers indexed here

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Sep 2026

Multiscale Regulation of Meiotic Recombination in Mammals.

Meiotic recombination is a multilayered process that shapes genetic diversity while safeguarding genome stability. In mammals, the final distribution of crossovers and non-crossovers emerges from the integration of sequence-specific hotspot specification, chromosome architecture, replication timing, and crossover patte...

Najma Shaheen, Andrea Marton Menendez, F. Pratto · 0 citations
Open access Jul 2026

High-resolution chromatin mapping reveals that CTCF anchors meiotic loops to the chromosome axis

High-resolution chromatin contact maps from mouse sperm precursors are used to reveal an intermediate folding state for chromosomes prior to meiotic entry and identify distinct looping positions associated with CTCF, supporting a model where meiotic loops are formed by association of existing loops modulated by CTCF ra...

Gang Cheng, Xin Li, Kevin Brick et al. · 0 citations

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