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Author

F. Operto

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Review Open access Sep 2026

Access to ketogenic dietary therapies for drug-resistant epilepsy in Italy: Insights from a LICE national survey.

OBJECTIVE Ketogenic dietary therapies (KDTs) are an established treatment option for drug-resistant epilepsy (DRE), yet their implementation in routine clinical practice remains heterogeneous. We conducted a national survey promoted by the Italian League Against Epilepsy (LICE) Dietary Therapy Study Group to evaluate c...

Tullio Messana, Nicolas Battistella, Valentina Biagioli et al. · 0 citations
Open access Sep 2026

Cenobamate Improves Emotional Dysregulation, Impulsivity, and Apathy in Drug-Resistant Focal Epilepsy: A Longitudinal Neuropsychological Study.

INTRODUCTION Although effects on cognitive function have been reported during cenobamate (CNB) treatment, far less is known about how it may affect neuropsychological domains such as apathy, emotion dysregulation, and impulsivity. This prospective longitudinal study aims to assess psychopathological and cognitive chang...

I. Sammarra, Adriana Saraceno, Iolanda Martino et al. · 0 citations
Open access Sep 2026

Neurocognitive endophenotypes in neurodevelopmental disorders: social cognition and executive functions in children with Autism Spectrum Disorder Level 1 and Attention-Deficit/Hyperactivity Disorder

Introduction Executive Functions (EF) and Social Cognition (SC) show strong interdependence, yet it remains unclear whether social difficulties in neurodevelopmental disorders, such as Autism Spectrum Disorder Level 1 (ASD1) and Attention Deficit/Hyperactivity Disorder (ADHD), arise from shared EF related mechanisms or...

G. Pastorino, Miriam Olivieri, Antonio Aquino et al. · 0 citations
Open access Aug 2026

Impact of Age on the Diagnostic Yield of Routine EEG in People With Childhood or Juvenile Absence Epilepsy: A Cross-Sectional Study.

Age significantly reduces the diagnostic yield of rEEG in CAE and JAE, regardless of ASM treatment, and Youden's exploratory analysis identified ≥ 14 years as the optimal threshold for predicting a rEEG negative.

F. Fortunato, A. Giugno, M. Sturniolo et al. · 0 citations
Open access Jul 2026

Expanding clinical variability in FBXW7-related neurodevelopmental disorder: a multicenter case series

A retrospective multicenter case series of seven previously unreported individuals with heterozygous FBXW7 variants identified through clinical genetic testing expands the phenotypic spectrum associated with FBXW7-related neurodevelopmental disorder and highlights variable expressivity and incomplete penetrance.

Salvatore Savasta, F. Comisi, G. Dell’Isola et al. · 0 citations

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